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New Engl J Med. \uff08\u6d77\u5916\u306e\u6709\u540d\u533b\u5b66\u96d1\u8a8c\uff09\u306b\u65e2\u611f\u67d3\u8005\uff08\u6210\u4eba\uff09\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u30a4\u30bf\u30ea\u30a2\u306b\u304a\u3044\u3066\u3001\u65e2\u611f\u67d338\u540d\u3092\u542b\u3080100\u540d\u3092\u5bfe\u8c61\u306b\u3057\u305f\u7814\u7a76\u3067\u3059\u3002\uff11\uff10\uff10\u540d\u306b\u30d5\u30a1\u30a4\u30b6\u30fc\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u3001\u65e2\u611f\u67d3\u8005\u306f1\u56de\u76ee\u306e\u63a5\u7a2e10\u65e5\u5f8c\u306b\u3001\u975e\u611f\u67d3\u8005\u306f2\u56de\u76ee\u306e\u63a5\u7a2e10\u65e5\u5f8c\u306b\u6297\u4f53\u5024\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u3001\u4e2d\u548c\u6297\u4f53\u306f\u65e2\u611f\u67d3\u8005\u306f1\u56de\u63a5\u7a2e\u3067\u529b\u4fa1569\u3001\u672a\u611f\u67d3\u8005\u306f2\u56de\u63a5\u7a2e\u3067\u529b\u4fa1118\u3068\u6709\u610f\u306a\u5dee\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u65e2\u611f\u67d3\u8005\u306f\u611f\u67d3\u304b\u3089\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u307e\u3067\u306e\u671f\u9593\u3067\uff11\uff5e2\u30ab\u6708\u306e\u7fa48\u540d\u30012\u30ab\u6708\u4ee5\u4e0a\uff5e3\u30ab\u6708\u306e\u7fa4\uff117\u540d\u30013\u30ab\u6708\u4ee5\u4e0a\u306e\u7fa412\u540d\u306e3\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u985e\u3057\u89e3\u6790\u3057\u305f\u3068\u3053\u308d\u3001\u529b\u4fa1\u306f\u9806\u306b437\u3001559\u3001694\u3067\u3057\u305f\u3002\u3088\u3063\u3066\u611f\u67d3\u5f8c3\u30ab\u6708\u4ee5\u4e0a\u7d4c\u904e\u3057\u3066\u304b\u3089\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f\u5834\u5408\u3001\u30d6\u30fc\u30b9\u30bf\u30fc\u52b9\u679c\uff08\u8ffd\u52a0\u514d\u75ab\u52b9\u679c\uff09\u304c\u3088\u308a\u9855\u8457\u306b\u73fe\u308c\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u4ee5\u4e0a\u3088\u308a\u65e2\u611f\u67d3\u8005\u306f\uff11\u56de\u63a5\u7a2e\u3067\u5341\u5206\u306a\u6297\u4f53\u7523\u751f\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002
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4\/30\u306e\u5165\u9662\u60a3\u8005\u6570
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4\/23\u306e\u5165\u9662\u60a3\u8005\u6570
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